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J Clin Microbiol. 2013 Aug;51(8):2735-8. doi: 10.1128/JCM.02649-12. Epub 2013 May 29.

Meropenem resistance in imipenem-susceptible meropenem-resistant Klebsiella pneumoniae isolates not detected by rapid automated testing systems.

Author information

1
Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Minami-ku, Hiroshima City, Hiroshima, Japan.

Abstract

Klebsiella pneumoniae showing high resistance to all β-lactams except imipenem, designated as ISMRK (imipenem-susceptible meropenem-resistant Klebsiella) is emerging in Japan. The carbapenem resistance of ISMRK cannot be screened by the Vitek and the RAISUS rapid automated susceptibility test systems, which may lead to inappropriate antimicrobial therapy, resulting in compromised patient outcomes.

PMID:
23720796
PMCID:
PMC3719643
DOI:
10.1128/JCM.02649-12
[Indexed for MEDLINE]
Free PMC Article

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