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J Clin Microbiol. 2013 Aug;51(8):2732-4. doi: 10.1128/JCM.00847-13. Epub 2013 May 29.

Use of Vitek 2 antimicrobial susceptibility profile to identify mecC in methicillin-resistant Staphylococcus aureus.

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1
Department of Medicine, University of Cambridge, Cambridge, United Kingdom.

Abstract

The emergence of mecC methicillin-resistant Staphylococcus aureus (MRSA) poses a diagnostic challenge for clinical microbiology laboratories. Using the Vitek 2 system, we tested a panel of 896 Staphylococcus aureus isolates and found that an oxacillin-sensitive/cefoxitin-resistant profile had a sensitivity of 88.7% and a specificity of 99.5% for the identification of mecC MRSA isolates. The presence of the mecC gene, determined by bacterial whole-genome sequencing, was used as the gold standard. This profile could provide a zero-cost screening method for identification of mecC-positive MRSA strains.

PMID:
23720794
PMCID:
PMC3719650
DOI:
10.1128/JCM.00847-13
[Indexed for MEDLINE]
Free PMC Article
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