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Clin Perinatol. 2013 Jun;40(2):201-14. doi: 10.1016/j.clp.2013.02.002.

The biology of retinopathy of prematurity: how knowledge of pathogenesis guides treatment.

Author information

1
Department of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA. Lois.Smith@childrens.harvard.edu

Abstract

Retinopathy of prematurity occurs because the retina of a preterm infant at birth is incompletely vascularized, and if the postnatal environment does not match the in utero environment that supported retinal development, the vessels and neural retina will not grow normally. Risk factors determined from many clinical studies and animal studies fall into 2 categories: prenatal factors and postnatal factors.

PMID:
23719305
PMCID:
PMC3673697
DOI:
10.1016/j.clp.2013.02.002
[Indexed for MEDLINE]
Free PMC Article

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