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Virology. 1990 Aug;177(2):807-11.

The hemagglutinating glycoproteins of influenza B and C viruses are acylated with different fatty acids.

Author information

1
Institut für Virologie, Philipps-Universität Marburg, Federal Republic of Germany.

Abstract

We present evidence that the hemagglutinin (HA) of influenza B virus and the glycoprotein of influenza C virus (HEF) are acylated. The fatty acid linkage is sensitive to treatment with hydroxylamine and mercaptoethanol, which points to a labile thioester-type linkage. The HA of influenza B virus contains mainly palmitic acid, whereas the HEF glycoprotein of influenza C virus is acylated with stearic acid which has not been observed before as the prevailing fatty acid in viral or cellular acyl proteins.

PMID:
2371783
DOI:
10.1016/0042-6822(90)90554-5
[Indexed for MEDLINE]

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