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J Conserv Dent. 2013 Mar;16(2):92-8. doi: 10.4103/0972-0707.108173.

Vital pulp therapy using calcium-enriched mixture: An evidence-based review.

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Iranian Center for Endodontic Research, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


Worldwide, casecontrol studies have revealed that the treatment outcomes of root canal therapy (RCT) are generally favorable; however, the overall epidemiological success rate of RCT in the general population is relatively low. On the other hand, vitality of dental pulp is a key factor in the long-term prognosis of permanent teeth; in recent years, vital pulp therapy (VPT) has received significant consideration as it has been revealed that the inflamed pulp has the potential to heal. In this review article, the current best evidence with regard to VPT using calcium-enriched mixture (CEM) cement in human permanent/primary teeth is discussed. A strategy based on a search using keywords for CEM cement as well as VPT was applied.


CEM cement; Calcium-enriched mixture; endodontic; pulp cap; pulpitis; pulpotomy; vital pulp therapy

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