Format

Send to

Choose Destination
Clin Exp Allergy. 2013 Jun;43(6):586-98. doi: 10.1111/cea.12023.

Cytokine regulation of the epidermal barrier.

Author information

1
MRC Human Immunology Unit, University of Oxford, John Radcliffe Hospital, Oxford, UK.

Abstract

Studies published in recent years have highlighted the role of epidermal barrier defects in both atopic skin disease and the development of broader allergic manifestations. While genetic determinants of barrier function are important, it is clear that local acquired effects are also involved in disease pathogenesis. In this review, we aimed to summarize the known influences of cytokines abundantly expressed during atopic skin disease on components of epidermal barrier integrity and function.

PMID:
23711120
DOI:
10.1111/cea.12023
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center