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Cardiovasc Psychiatry Neurol. 2013;2013:159850. doi: 10.1155/2013/159850. Epub 2013 Apr 27.

A systematic review of depression and anxiety in patients with atrial fibrillation: the mind-heart link.

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Mercy Street Vincent's Medical Center, 2213 Cherry St., Toledo, OH 43608, USA.


Atrial fibrillation (AF) is the most commonly seen arrhythmia in clinical practice. At present, few studies have been conducted centering on depression and anxiety in AF patients. Our aim in this systematic review is to use the relevant literature to (1) describe the prevalence of depression and anxiety in AF patients, (2) assess the impact that depression and anxiety have on illness perception in patients with AF, (3) provide evidence to support a hypothetical connection between the pathophysiology of AF and depression and anxiety, (4) evaluate the benefit of treatment of AF on depression and anxiety, and (5) give insight on medically managing a patient with AF and concomitant depression and anxiety.

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