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ScientificWorldJournal. 2013 Apr 9;2013:825375. doi: 10.1155/2013/825375. Print 2013.

Hepatitis C virus infection: looking for interferon free regimens.

Author information

1
Internal Medicine-Infectious Diseases Department, Hospital Son Llàtzer, Carretera de Manacor, Km 4, 07198 Palma de Mallorca, Spain. jgonzalez4@hsll.es

Abstract

Recent developments of new drugs' combinations are changing the treatment paradigm in hepatitis C virus infection. Due to the side effect profile of pegylated interferons, interferon-sparing regimens have become the main target in chronic hepatitis C treatment research. Recent proofs of concept studies have suggested that cure of chronic hepatitis C can be achieved without interferon. The purpose of this paper is to provide an overview of the clinical results recently reported for the treatment of hepatitis C virus infection with interferon-free regimens, focusing on the most promising new compounds and combinations.

PMID:
23710151
PMCID:
PMC3654259
DOI:
10.1155/2013/825375
[Indexed for MEDLINE]
Free PMC Article
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