Format

Send to

Choose Destination
See comment in PubMed Commons below
J Glaucoma. 2014 Sep;23(7):441-5. doi: 10.1097/IJG.0b013e3182946522.

Remnants of the anterior tunica vasculosa lentis and long anterior lens zonules.

Author information

1
*Department of Clinical Education, Illinois Eye Institute, Illinois College of Optometry and Departments of †Epidemiology and Biostatistics ‡Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL.

Abstract

PURPOSE:

To investigate presence of remnants of the tunica vasculosa lentis, a possible indication of anterior segment dysgenesis, in subjects with the long anterior zonule (LAZ) trait.

METHODS:

Retroillumination photographs of the pupil region had been collected in earlier study of the LAZ trait in African Americans. Secondary image analysis was performed to assess the frequency of intact persistent pupillary membrane iris strands (PPMIS).

RESULTS:

The analysis included 148 subjects, comprised of 74 LAZ subjects (median age=70 y; range, 50 to 91 y; 64 females) and 74 controls (68 y; 50 to 83 y; 64 females). While controlling for age and sex, analysis showed that LAZ subjects were 3.1 times more likely than controls (odds ratio=3.1; 95% confidence interval, 1.4-6.7; P=0.004) to exhibit PPMIS in at least one of their eyes.

CONCLUSION:

The LAZ trait, which is being studied as a potential risk factor for glaucoma, was associated with presence of PPMIS in our study population.

PMID:
23708424
PMCID:
PMC3796137
DOI:
10.1097/IJG.0b013e3182946522
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wolters Kluwer Icon for PubMed Central
    Loading ...
    Support Center