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Cell. 2013 May 23;153(5):939-40. doi: 10.1016/j.cell.2013.04.051.

New balance in pluripotency: reprogramming with lineage specifiers.

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1
Stem Cell Unit, Department of Genetics, Silberman Institute of Life Sciences, The Hebrew University, Jerusalem 91904, Israel.

Abstract

Induction of pluripotency in somatic cells has been achieved by myriad combinations of transcription factors that belong to the core pluripotency circuitry. In this issue, Shu et al. report reprogramming with lineage specifiers, lending support to the view of the pluripotent state as a fine balance between competing differentiation forces.

PMID:
23706730
DOI:
10.1016/j.cell.2013.04.051
[Indexed for MEDLINE]
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