Format

Send to

Choose Destination
See comment in PubMed Commons below
J Korean Acad Nurs. 2013 Apr;43(2):287-95. doi: 10.4040/jkan.2013.43.2.287.

[Risk factors and clinical outcomes for vancomycin-resistant enterococcus colonization on intensive care unit admission].

[Article in Korean]

Author information

1
Infection Control Team, Dong-A University Medical Center, Busan, Korea.

Abstract

PURPOSE:

The purpose of this study was to identify vancomycin-resistant enterococcus (VRE) colonization rate in patients admitted to the intensive care unit (ICU), associated risk factors and clinical outcomes for VRE colonization.

METHODS:

Of the 7,703 patients admitted to the ICUs between January, 2008 and December, 2010, medical records of 554 VRE colonized and 503 uncolonized patients were reviewed retrospectively. To analyzed the impact of colonization on patients' clinical outcomes, 199 VRE colonized patients were matched with 199 uncolonized patients using a propensity score matching method.

RESULTS:

During the study period, 567 (7.2%) of the 7,703 patients were colonized with VRE. Multivariate analysis identified the following independent risk factors for VRE colonization: use of antibiotics (odds ratio [OR]=3.33), having bedsores (OR=2.92), having invasive devices (OR=2.29), methicillin-resistant Staphylococcus aureus co-colonization (OR=1.84), and previous hospitalization (OR=1.74). VRE colonized patients were more likely to have infectious diseases than uncolonized patients. VRE colonization was associated with prolonged hospitalization and higher mortality.

CONCLUSION:

Strict infection control program including preemptive isolation for high-risk group may be helpful. Further research needs to be done to investigate the effects of active surveillance program on the incidence of colonization or infection with VRE in the ICU.

KEYWORDS:

Enterococcus; Infection control; Intensive care units; Vancomycin resistance

PMID:
23703606
DOI:
10.4040/jkan.2013.43.2.287
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Korean Society of Nursing Science
    Loading ...
    Support Center