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Clin Cosmet Investig Dermatol. 2013 May 15;6:127-35. doi: 10.2147/CCID.S43141. Print 2013.

The skin landscape in diabetes mellitus. Focus on dermocosmetic management.

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Laboratory of Skin Bioengineering and Imaging (LABIC), University of Liège, Liège, Belgium.



Some relationships are established between diabetes mellitus (DM) and a series of cutaneous disorders. Specific dermatoses are markers for undiagnosed DM. Other disorders represent supervening complications in an already treated DM patient.


To review the information about dermocosmetic care products and their appropriate use in the management and prevention of dermatoses related to DM.


The peer-reviewed literature and empiric findings are covered. Owing to the limited clinical evidence available for the use of dermocosmetics, a review of the routine practices and common therapies in DM-related dermatoses was conducted.


Some DM-related dermatoses (acanthosis nigricans, pigmented purpuric dermatosis) are markers of macrovascular complications. The same disorders and some others (xerosis, Dupuytren's disease) have been found to be more frequently associated with microangiopathy. Other skin diseases (alopecia areata, vitiligo) were found to be markers of autoimmunity, particularly in type 1 DM. Unsurprisingly, using dermocosmetics and appropriate skin care has shown objective improvements of some DM-related dermatoses, such effects improve the quality of life. The most common skin manifestations of DM fall along continuum between "dry skin," xerosis, and acquired ichthyosis, occurring predominately on the shins and feet. Dermocosmetic products improve the feeling of well-being for DM patients.


dermocosmetics; diabetes mellitus; diabetic xerosis; skin

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