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Int J Emerg Med. 2013 May 21;6(1):16. doi: 10.1186/1865-1380-6-16.

Non-traumatic splenic rupture in a patient on oral anticoagulation.

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Department of Emergency Medicine, Leiden University Medical Centre, Albinusdreef 2, 2333 Leiden, ZA, the Netherlands.



Splenic injury is normally associated with trauma, but spontaneous splenic rupture has been described in various systemic diseases.


A 56-year-old male on oral anticoagulation presented to the emergency department with epigastric pain, nausea, and left upper quadrant tenderness. There was no history of trauma. Contrast-enhanced CT imaging revealed a large subcapsular haematoma of the spleen. Oral anticoagulation was antagonised with vitamin K and the patient was discharged in good condition after 3 days of clinical observation.


Non-traumatic splenic rupture is a rare complication of oral anticoagulation.

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