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Arthritis Rheum. 1990 Jul;33(7):970-7.

Contribution of renal biopsy data in predicting outcome in lupus nephritis. Analysis of 116 patients.

Author information

1
Department of Rheumatology, Dr. Daniel den Hoed Clinic, Rotterdam, The Netherlands.

Abstract

We reassessed renal biopsy specimens from 116 patients with systemic lupus erythematosus and clinical manifestations of lupus nephritis to determine the contributions of the World Health Organization classification system, the activity and chronicity indexes of the National Institutes of Health scoring system, and various clinical parameters at the time of biopsy to predicting disease outcome. Multivariate analysis showed that only a chronicity index greater than 3 was predictive for decreased renal survival, while age greater than 31 years at biopsy and a chronicity index greater than 3 were associated with decreased patient survival. Clinical tests of renal function were not reliable in discriminating between active lesions and chronic renal damage.

PMID:
2369432
DOI:
10.1002/art.1780330708
[Indexed for MEDLINE]

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