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Cancer Biol Med. 2013 Mar;10(1):43-6. doi: 10.7497/j.issn.2095-3941.2013.01.007.

Spontaneous pineal apoplexy in a pineal parenchymal tumor of intermediate differentiation.

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Nepean Hospital, Kingswood, NSW 2747, Australia;


Pineal apoplexy is a rare clinical presentation of pineal parenchymal tumors. We report the curative treatment of a case of pineal parenchymal tumor of intermediate differentiation with spontaneous apoplectic hemorrhage. This case is shown through computed tomography and magnetic resonance imaging of the brain, and is confirmed via histopathological studies. Recurrent upward gaze paresis was observed after the stereotactic biopsy. The paresis required an expeditious tumor resection. The mechanism of the pineal apoplectic hemorrhage remains unclear although it has been observed in different pineal region lesions. Clinical and radiological evidence of the cure 5 years post-surgery is available.


Apoplexy; Parinaud’s syndrome; obstructive hydrocephalus; pineal gland; pineal parenchymal tumor

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