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Stroke. 2013 Aug;44(8):2324-6. doi: 10.1161/STROKEAHA.113.001355. Epub 2013 May 16.

Influence of chronic ethanol consumption on the neurological severity in patients with acute cerebral ischemia.

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1
University of Lille Nord de France, CHU Lille, Lille, France.

Abstract

BACKGROUND AND PURPOSE:

We tested the hypothesis that excessive chronic ethanol consumption is associated with more severe ischemic strokes.

METHODS:

We recruited patients with supratentorial cerebral ischemia within 48 hours of symptom onset. We defined heavy drinkers by a weekly consumption of ethanol of ≥300 g and severe strokes by a National Institutes of Health Stroke Scale score≥6.

RESULTS:

Of 436 patients, 60 were heavy drinkers. Being a heavy drinker was independently associated with baseline National Institutes of Health Stroke Scale scores≥6 (odds ratio, 2.35; 95% confidence interval, 1.12-5.26; P=0.023) at the logistic regression analysis. This result was not modified with the propensity analysis.

CONCLUSION:

An excessive chronic ethanol consumption is associated with higher baseline stroke severity.

KEYWORDS:

NIHSS score; alcohol; cerebral ischemia; stroke severity

PMID:
23686975
DOI:
10.1161/STROKEAHA.113.001355
[Indexed for MEDLINE]
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