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Acta Neurochir (Wien). 2013 Jul;155(7):1229-34. doi: 10.1007/s00701-013-1739-4. Epub 2013 May 18.

Primary extraosseous intradural spinal Ewing's sarcoma: report of two cases.

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Department of Neurological Surgery, Hospital Universitario La Fe, Área Administrativa 5E, c/Bulevar Sur, s/n, 46026, Valencia, Spain.


Two cases of primary extraosseous intradural spinal Ewing's sarcoma are reported with a review of the current literature. This rare neoplasm shares features with cerebral primitive neuroectodermal tumors, complicating a correct diagnosis. Gross total resection seems to be the main treatment, although adjuvant therapies could improve the prognosis. In case 1, a 56-year-old man presented with cauda equina syndrome. MRI showed an intradural tumor from L4 to S2. An emergency laminectomy was performed with gross total resection of a hemorrhagic tumor, followed by adjuvant treatment. In the second case, a 25-year-old female developed leg and lumbar pain. MRI study identified a homogeneously enhancing intradural mass at the L2-L3 level. A laminoplasty was performed, followed by tumor resection; no adjuvant treatment was administered afterwards. Immunohistochemical workup confirmed the diagnosis of Ewing's sarcoma in both cases.

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