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Clin Endocrinol (Oxf). 2014 Jan;80(1):141-7. doi: 10.1111/cen.12247. Epub 2013 Jun 12.

Goitre and urinary iodine excretion survey in schoolchildren of Kashmir Valley.

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  • 1Department of Endocrinology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India.

Abstract

BACKGROUND:

An extensive survey on schoolchildren in Kashmir Valley in 1995 showed a high prevalence of goitre, making it imperative to have a relook at our iodine status, 15 years postiodization.

OBJECTIVE:

To study the total prevalence of goitre and urinary iodine excretion (UIE) in Kashmiri schoolchildren, 15 years postiodization.

DESIGN:

A cross-sectional survey, covering 9576 schoolchildren, aged 5-15 years (5988 in 6-12 year age group) was conducted. Goitres were graded as per WHO/UNICEF/ICCIDD. UIE was measured by the arsenic acid reduction in ceric ions method and was estimated in 208 subsampled children. Results were compared with that of 1995 survey.

RESULTS:

The overall prevalence of goitre in the present study was 3·8% (95% CI: 3·4-4·2) and 3·7% (95% CI: 3·2-4·2) in those aged 6-12 years. No significant difference in prevalence of goitre was observed between boys and girls overall (3·6% vs 4·1%. P > 0·2), nor in the 6-12 year age group (3·3% vs 4·0%, P > 0·1). There was a significant trend of increasing prevalence of goitre with age (P < 0·005). UIE ranged from 12 to 397 μg/g.creatinine (median, 104); 11% subjects had UIE of <50 μg/g.creatinine. Overall, prevalence of goitre was significantly lower (3·8% vs 45·2%, P < 0·001), and mean UIE was significantly higher (123·6 ± 5·3 vs 49·60 ± 3·55 μg/g.creatinine, P < 0·001), compared to that in the 1995 survey.

CONCLUSION:

The marked improvement in overall iodine nutrition in Kashmir Valley- one and a half decades after implementation of salt iodization should encourage healthcare providers to make tangible efforts for implementation of iodization programmes in areas with iodine deficiency.

PMID:
23679109
DOI:
10.1111/cen.12247
[PubMed - indexed for MEDLINE]
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