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Clin Pediatr (Phila). 2013 Sep;52(9):821-8. doi: 10.1177/0009922813488644. Epub 2013 May 14.

Effects of hypothetical type 2 diabetes genetic testing on parents' efforts to prevent diabetes in children.

Author information

1
Child Health Evaluation and Research, University of Michigan, Ann Arbor, MI 48109-5456, USA. btarini@umich.edu

Abstract

OBJECTIVE:

To examine the effect of hypothetical genetic susceptibility test results on diabetic parents' intention to prevent type 2 diabetes (T2D) in their children.

METHODS:

Parents with T2D indicated their intention to prevent T2D in their youngest child at baseline and after a hypothetical positive and negative T2D genetic test result. We calculated mean/median "preventive intention scores" for each scenario and examined the association between parents' score change and parent/child characteristics.

RESULTS:

A total of 63% of parents reported that their child had "almost no risk" or "slight risk" of developing T2D. Parents' median baseline preventive intention score was 8. It increased to 10 after a positive test result and decreased to 5 after a negative test result.

CONCLUSIONS:

Negative T2D genetic susceptibility test results may decrease diabetic parents' intentions to prevent T2D for their children. Future research studies in a real-life clinical context should examine this phenomenon.

KEYWORDS:

children; diabetes mellitus; genetic testing; type 2 diabetes; vignettes

PMID:
23676285
PMCID:
PMC4035702
DOI:
10.1177/0009922813488644
[Indexed for MEDLINE]
Free PMC Article
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