Format

Send to

Choose Destination
PLoS One. 2013 May 10;8(5):e62848. doi: 10.1371/journal.pone.0062848. Print 2013.

The use of sub-mental ultrasonography for identifying patients with severe obstructive sleep apnea.

Author information

1
Department of Traumatology, National Taiwan University Hospital, Taipei City, Taiwan.

Abstract

OBJECTIVE:

This study aimed to explore the association between obstructive sleep apnea (OSA) severity and pharyngeal parameters using sub-mental ultrasonography (US), and investigate the accuracy of US for identifying severe OSA patients.

METHODS:

One hundred and five consecutive referrals for suspected OSA were enrolled. The diameters of the retro-glossal (RG) and retro-palatal (RP) regions were measured via sub-mental US upon expiration during tidal breathing, forced inspiration, and Müller maneuver (MM). Independent factors associated with severe OSA identified from two-thirds of randomly-selected patients (model-development group) were used to construct a model for predicting severe OSA. The accuracy of the model was validated in the remaining one-third of patients (validation group).

RESULTS:

Fifty severe OSA patients, 30 with mild-moderate OSA, and 25 without OSA were enrolled. Compared to non-OSA and mild-moderate OSA patients, those with severe OSA had narrower RP diameter in all three maneuvers. Using the prediction model constructed with changes of RP diameters at MM and neck circumference, the independent predictors of severe OSA in the model-development group had 100% sensitivity and 65% specificity.

CONCLUSION:

Sub-mental US can accurately discriminate the severity of OSA and be used to identify patients with severe OSA.

TRIAL REGISTRATION:

ClinicalTrials.gov NCT00674076.

PMID:
23675433
PMCID:
PMC3651088
DOI:
10.1371/journal.pone.0062848
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Public Library of Science Icon for PubMed Central
Loading ...
Support Center