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Indian Pediatr. 2013 Apr;50(4):424-6.

Precocious puberty as initial presentation in mediastinal tumour.

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1
Division of Pediatric Oncology, Regional Cancer Centre, Trivandrum, Kerala, India. drmanjushanair@gmail.com

Abstract

Numerous disorders can cause precocious puberty in children, and germ cell tumours (GCT) are one of the rare causes . We report two cases of mediastinal malignant GCTs who presented with precocious puberty. Both patients had bulky and advanced disease, were aggressively treated with neo-adjuvant chemotherapy and surgery, and are surviving and free of disease.

PMID:
23665606
[Indexed for MEDLINE]
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