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Ann Maxillofac Surg. 2013 Jan;3(1):95-7. doi: 10.4103/2231-0746.110079.

Non-Hodgkin's lymphoma of maxillary sinus: An unusual presentation.

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Department of Oral and Maxillofacial Surgery, VYWS Dental College and Hospital, Maharashtra, India.


Non-Hodgkin's Lymphoma (NHL) are a group of neoplasms that originate from the cells of the lymphoreticular system. Forty percent of Non-Hodgkin's lymphoma arises from extranodal sites. The nasal cavities and paranasal sinuses are rarely affected by primary NHL. Common primary extranodal sites of lymphomas include stomach, liver, soft tissue, dura, bone, intestine and bone marrow. Most patients present with rapidly enlarging masses, often with symptoms both locally and systemically (fever, recurrent night sweats, or weight loss). The vast majority of patients with localized disease are curable with combined modality therapy or combination chemotherapy alone. About 50% patients are cured with doxorubicin based combination chemotherapy and rituximab. An atypical case of extranodal Non-Hodgkin's lymphoma of maxillary sinus is discussed.


Chemotherapy; diffuse large B-cell; immunohistochemistry; maxillary sinus; non-Hodgkin's lymphoma

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