Format

Send to

Choose Destination
See comment in PubMed Commons below
Pulm Circ. 2013 Jan;3(1):20-30. doi: 10.4103/2045-8932.109911.

Nitric oxide deficiency in pulmonary hypertension: Pathobiology and implications for therapy.

Author information

1
Department of Pulmonary, Allergy and Critical Care Medicine, Respiratory Institute, Cleveland, Ohio, USA.

Abstract

Nitric oxide (NO) is a diffusible gas with diverse roles in human physiology and disease. Significant progress in the understanding of its biological effects has taken place in recent years. This has led to a better understanding of the pathobiology of pulmonary hypertension (PH) and the development of new therapies. This article provides an overview of the NO physiology and its role in the pathobiology of lung diseases, particularly PH. We also discuss current and emerging specific treatments that target NO signaling pathways in PH.

KEYWORDS:

nitric oxide; physiopathology and therapeutics; pulmonary hypertension

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Support Center