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Prostaglandins Leukot Essent Fatty Acids. 2013 Jun;88(6):419-29. doi: 10.1016/j.plefa.2013.03.008. Epub 2013 May 6.

Omega-3 fatty acids are related to abnormal emotion processing in adolescent boys with attention deficit hyperactivity disorder.

Author information

1
Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King's College London, United Kingdom. rachel.gow@kcl.ac.uk

Abstract

BACKGROUND:

In addition to the core symptoms, attention deficit hyperactivity disorder (ADHD) is associated with poor emotion regulation. There is some evidence that children and young adults with ADHD have lower omega-3 levels and that supplementation with omega-3 can improve both ADHD and affective symptoms. We therefore investigated differences between ADHD and non-ADHD children in omega-3/6 fatty acid plasma levels and the relationship between those indices and emotion-elicited event-related potentials (ERPs).

METHODS:

Children/adolescents with (n=31) and without ADHD (n=32) were compared in their plasma omega-3/6 indices and corresponding ERPs during an emotion processing task.

RESULTS:

Children with ADHD had lower mean omega-3/6 and ERP abnormalities in emotion processing, independent of emotional valence relative to control children. ERP abnormalities were significantly associated with lower omega-3 levels in the ADHD group.

CONCLUSIONS:

The findings reveal for the first time that lower omega-3 fatty acids are associated with impaired emotion processing in ADHD children.

PMID:
23660373
PMCID:
PMC5559876
DOI:
10.1016/j.plefa.2013.03.008
[Indexed for MEDLINE]
Free PMC Article

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