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Cardiol Young. 2014 Jun;24(3):524-7. doi: 10.1017/S1047951113000565. Epub 2013 May 10.

The use of levosimendan in children with cancer with severe acute cardiac dysfunction: case series and a review of the literature.

Author information

1
1 Division of Critical Care Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
2
2 Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Abstract

We report the use of levosimendan in two febrile, neutropenic children with cancer - one post bone marrow transplant - with acute heart failure following chemotherapy. Initial management with epinephrine, milrinone, and diuresis was unsuccessful. Infusion of levosimendan without a loading dose was added to the ongoing heart failure therapy, which resulted in persistent symptomatic and echocardiographic improvement without major side effects.

PMID:
23659288
DOI:
10.1017/S1047951113000565
[Indexed for MEDLINE]

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