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Clin Appl Thromb Hemost. 2015 Jan;21(1):25-9. doi: 10.1177/1076029613488935. Epub 2013 May 7.

Relationship between neutrophil-to-lymphocyte ratio and saphenous vein graft disease in patients with coronary bypass.

Author information

1
Department of Cardiology, Diskapi Yildirim Bayezit Educational and Research Hospital, Ankara, Turkey drmehmetdogan@yahoo.com.
2
Department of Cardiology, Ankara Education and Research Hospital, Ankara, Turkey.
3
Department of Cardiology, Diskapi Yildirim Bayezit Educational and Research Hospital, Ankara, Turkey.

Abstract

PURPOSE:

In this study, we aimed to investigate the relationship between saphenous vein graft disease (SVGD) and neutrophil-to-lympocyte ratio (NLR) with other possible confounding factors.

METHODS:

A total of 120 patients were enrolled into the present study. Of all participants, 40 patients were with SVGD and 80 of them were with patent SVG.

RESULTS:

The NLR, white blood cell (WBC) count, age of SVG, red cell distribution width (RDW), and mean platelet volume were significantly higher in the SVGD group. In regression analysis, NLR, WBC, RDW, and age of SVG remained as independent predictors of SVGD.

CONCLUSION:

To our knowledge, we showed for the first time that NLR is independently associated with SVGD. It can be easily used in this era, because it is easily available, widely used, and relatively cheap. Besides NLR, WBC count, SVG age, and RDW can also be used to predict SVGD.

KEYWORDS:

inflammation; neutrophil-to-lymphocyte ratio; saphenous vein graft

PMID:
23653146
DOI:
10.1177/1076029613488935
[Indexed for MEDLINE]

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