Format

Send to

Choose Destination
Chemistry. 2013 Jun 17;19(25):8048-52. doi: 10.1002/chem.201300962. Epub 2013 May 6.

Tricycles by a new Ugi variation and Pictet-Spengler reaction in one pot.

Author information

1
Department of Pharmaceutical Science, University of Pittsburgh, BST-3, 3501 Fifth Ave, Pittsburgh, PA, USA.

Abstract

Subsequent mild cyclization of aromatic substrates by Pictet-Spengler condensation stereoselectively gave new tricyclic compounds. Examples are described in decent yields over two steps in one pot, and a crystal structure is also presented to support the proposed structures.

PMID:
23649922
PMCID:
PMC3740945
DOI:
10.1002/chem.201300962
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center