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BMJ Case Rep. 2013 May 2;2013. pii: bcr2013009516. doi: 10.1136/bcr-2013-009516.

A rheumatoid nodule in an unusual location: mediastinal lymph node.

Author information

1
Department of Rheumatology, Cooper Medical School of Rowan University, Camden, New Jersey, USA. yachouiralph@cooperhealth.edu

Abstract

Rheumatoid arthritis (RA) is a multisystem inflammatory disease characterised by destructive synovitis and varied extra-articular involvement. Rheumatoid lung nodules are the most common pulmonary manifestations of RA. Rheumatoid nodules in mediastinal lymph nodes are extremely uncommon. We describe a male patient with long-standing RA and subcutaneous rheumatoid nodules presenting with multiple lung nodules and mediastinal lymphadenopathies. Definite histopathology of a lymph node was consistent with necrobiotic granuloma due to RA. Clinicians should be aware of rheumatoid nodules as a potential cause of mediastinal lymphadenopathies, mainly in advanced rheumatoid arthritis.

PMID:
23645652
PMCID:
PMC3669837
DOI:
10.1136/bcr-2013-009516
[Indexed for MEDLINE]
Free PMC Article
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