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Nucleus. 2013 May-Jun;4(3):160-5. doi: 10.4161/nucl.24676. Epub 2013 Apr 15.

The cell biology of open and closed mitosis.

Author information

1
Institute of Biochemistry, Department of Biology, Swiss Federal Institute of Technology Zürich, Zürich, Switzerland.

Abstract

Mitosis is the process of one cell dividing into two daughters, such that each inherits a single and complete copy of the genome of their mother. This is achieved through the equal segregation of the sister chromatids between the daughter cells. However, beyond this simple principle, the partitioning of other cellular components between daughter cells appears to follow a large variety of patterns. We discuss here how the organization of the nuclear envelope during mitosis influences cell division and, subsequently, cellular identity.

KEYWORDS:

asymmetric cell division; closed mitosis; compartmentalization; nuclear envelope; open mitosis

PMID:
23644379
PMCID:
PMC3720745
DOI:
10.4161/nucl.24676
[Indexed for MEDLINE]
Free PMC Article

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