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Acta Paediatr. 2013 Sep;102(9):857-62. doi: 10.1111/apa.12280. Epub 2013 May 15.

The safety of statins in children.

Author information

1
Department of Cardiology, Mercato san Severino Hospital, Salerno, Italy. normanlamaida@libero.it

Abstract

Current American Academy of Pediatrics Guidelines recommended that statins should be considered as a first-line agent in children as early as 8 years of age. The aim of our work is to assess the safety of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in children with hypercholesterolaemia.

CONCLUSION:

Controlled studies in children show that statin monotherapy is efficacious, well tolerated and safe in the short-time. Unfortunately, these studies have relatively short-term follow-up periods, and therefore, long-term safety remains unclear.

KEYWORDS:

Children; HMG-CoA reductase inhibitors; Safety

PMID:
23631461
DOI:
10.1111/apa.12280
[Indexed for MEDLINE]

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