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Case Rep Neurol. 2013 Mar 21;5(1):52-5. doi: 10.1159/000350572. Print 2013 Jan.

Are steroids a beneficial adjunctive therapy in the immunosuppressed patient with herpes simplex virus encephalitis?

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Neurocritical Care Division, Department of Neurology, Miller School of Medicine, University of Miami, Miami, Fla., USA.


Few reports describe the reactivation of latent herpes simplex virus causing encephalitis (HSVE) in patients undergoing brain radiation therapy and a concomitant steroid regimen. The role for steroid use in the treatment of patients with HSVE has not been fully elucidated. We report the case of a female patient immunosuppressed by steroids and brain radiation who developed HSVE and responded to acyclovir and dexamethasone.


Corticosteroids; Herpes simplex virus encephalitis; Immunosuppression

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