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Emerg Infect Dis. 2013 Mar;19(3):471-4. doi: 10.3201/1903.121475.

Virulence of pertactin-negative Bordetella pertussis isolates from infants, France.

Author information

1
Institut Pasteur, Paris, France.

Abstract

Bordetella pertussis isolates that do not express pertactin (PRN) are increasing in regions where acellular pertussis vaccines have been used for >7 years. We analyzed data from France and compared clinical symptoms among infants <6 months old infected by PRN-positive or PRN-negative isolates. No major clinical differences were found between the 2 groups.

KEYWORDS:

Bordetella pertussis; acellular vaccines; bacteria; coccobacillus; immunization; pertactin; vaccination; vaccine

PMID:
23621904
PMCID:
PMC3647673
DOI:
10.3201/1903.121475
[Indexed for MEDLINE]
Free PMC Article

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