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J Ultrasound Med. 2013 May;32(5):825-33. doi: 10.7863/ultra.32.5.825.

Feasibility study of contrast-enhanced automated acoustic mammography.

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1
Department of Biomedical Engineering, Technion, Israel Institute of Technology, Technion City, 32000 Haifa, Israel.

Abstract

The feasibility of implementing image subtraction in through-transmission breast sonography was examined. Acoustic mammograms of women with suspicious findings were obtained using through-transmission imaging. Precontrast images were initially acquired. Then a perflutren liquid microsphere contrast agent solution was injected intravenously, and new sets of images were acquired. Precontrast-postcontrast subtraction images depicting the resulting changes were then obtained and visually compared with other imaging modalities. The ability to detect changes stemming from contrast agent injection in the through-transmission mode was verified. The comparability with x-ray mammography and magnetic resonance imaging was shown. Finally, the ability to compare images obtained before and several months after surgery was confirmed.

PMID:
23620325
DOI:
10.7863/ultra.32.5.825
[Indexed for MEDLINE]
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