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J Clin Microbiol. 2013 Jul;51(7):2396-9. doi: 10.1128/JCM.00151-13. Epub 2013 Apr 24.

Integrating the Xpert MTB/RIF assay into a diagnostic workflow for rapid detection of Mycobacterium tuberculosis in a low-prevalence area.

Author information

1
Institut für Medizinische Mikrobiologie, Universität Zürich, Zürich, Switzerland.

Abstract

The Xpert MTB/RIF assay is a rapid and fully automated real-time PCR assay. The performance of the Xpert MTB/RIF assay as a primary screening test for urgent clinical specimens was evaluated during a 2-year period. The results showed that replacing smear microscopy with the Xpert MTB/RIF assay facilitates laboratory handling and improves the sensitivity and specificity of Mycobacterium tuberculosis detection.

PMID:
23616455
PMCID:
PMC3697699
DOI:
10.1128/JCM.00151-13
[Indexed for MEDLINE]
Free PMC Article

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