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Genomics Inform. 2013 Mar;11(1):7-14. doi: 10.5808/GI.2013.11.1.7. Epub 2013 Mar 31.

Perspectives of international human epigenome consortium.

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1
Division of Structural and Functional Genomics, Center for Genome Sciences, Korea National Institute of Health, Cheongwon 363-951, Korea.

Abstract

As the International Human Epigenome Consortium (IHEC) launched officially at the 2010 Washington meeting, a giant step toward the conquest of unexplored regions of the human genome has begun. IHEC aims at the production of 1,000 reference epigenomes to the international scientific community for next 7-10 years. Seven member institutions, including South Korea, Korea National Institute of Health (KNIH), will produce 25-200 reference epigenomes individually, and the produced data will be publically available by using a data center. Epigenome data will cover from whole genome bisulfite sequencing, histone modification, and chromatin access information to miRNA-seq. The final goal of IHEC is the production of reference maps of human epigenomes for key cellular status relevant to health and disease.

KEYWORDS:

DNA methylayion; chromatin; histones; methylome; microRNAs

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