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Diabetes. 2013 May;62(5):1405-8. doi: 10.2337/db12-1610.

Glucose variability: where it is important and how to measure it.

Author information

1
Academic Medical Center at the University of Amsterdam, Amsterdam, the Netherlands. j.h.devries@amc.uva.nl

Abstract

Glucose variability predicts hypoglycemia in both type 1 and type 2 diabetes and has consistently been related to mortality in nondiabetic patients in the intensive care unit. SD and mean amplitude of glycemic excursions have historically been very popular measures of glucose variability. For reasons outlined in this counterpoint, I propose to use coefficient of variation and the mean absolute glucose change as preferred measures of glucose variability.

PMID:
23613566
PMCID:
PMC3636643
DOI:
10.2337/db12-1610
[Indexed for MEDLINE]
Free PMC Article

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