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Ann Thorac Surg. 2013 May;95(5):1797-9. doi: 10.1016/j.athoracsur.2012.09.039.

Ectopic Cushing's syndrome secondary to pulmonary carcinoid tumor.

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Tuberculosis and Lung Diseases Research Center, Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.


Adrenocorticotropic hormone (ACTH) overproduction within the pituitary gland or ectopically leads to hypercortisolism. In this study a case of Cushing's syndrome caused by an ectopic ACTH-secreting carcinoid tumor in lung is discussed, as are the available diagnostic procedures. The patient was a 28-year-old woman with clinical features starting about 6 months previously. The results of her biochemical tests suggested ectopic Cushing's syndrome. Full-body computed tomography revealed a single nodule in the inferior lobe of the right lung. After removal of the nodule, the patient's symptoms subsided clinically, and laboratory tests confirmed remission of the hypercortisolism.

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