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BMJ Case Rep. 2013 Apr 18;2013. pii: bcr2013009308. doi: 10.1136/bcr-2013-009308.

Anaplastic large T-cell lymphoma presenting as an isolated osseous involvement: a case report and review of the literature.

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1
Department of Medicine, Maulana Azad Medical College, New Delhi, India. drhemantnayak@gmail.com

Abstract

This case describes a 50-year-old man with multiple lytic bone lesions involving the skull, pelvis and ribs and associated features of anaemia, hypercalcaemia, azotaemia and subsequently found to be non-Hodgkin's lymphoma of anaplastic large T cell type (ALCL) on biopsy taken from a soft tissue mass in the anterior chest wall as an aetiology. We report this case with an aim to expand our knowledge of isolated osseous involvement in case of non-Hodgkin's lymphoma. This case was unique in the sense of an isolated osseous involvement in ALCL without any organomegaly and lymphadenopathy with a normal bone marrow biopsy finding. So in rare instances, T-cell lymphoma can present with a multiple lytic lesion, anaemia, hypercalcaemia. Although B-cell non-Hodgkin's lymphoma can present with the above manifestation, it is extremely rare for T-cell non-Hodgkin's lymphoma.

PMID:
23605839
PMCID:
PMC3645231
DOI:
10.1136/bcr-2013-009308
[Indexed for MEDLINE]
Free PMC Article
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