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Bull Environ Contam Toxicol. 2013 Jun;90(6):742-9. doi: 10.1007/s00128-013-0998-3. Epub 2013 Apr 20.

Outline of occupational chromium poisoning in China.

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Post-doctoral Research Stations, Nephrology Institute, The Second Xiangya Hospital, Central South University, Changsha Hunan 410011, China.


The present study analyzed the feature of occupational chromium poisoning in China since the 1980s. The collected data were acquired from 18 previous surveys of chromium poisoning in 14 cities of China. The method of risk assessment was applied to calculate the relative risk and 95% CI, p < 0.05 was considered as a significant risk. The results showed that nasal disease was the most common sign of occupational chromium poisoning, and the prevalence rate of nasal disease was 17.83% in total population of 6,998. Further, the risk analysis showed that occupational chromium poisoning led to an increased risk of lung or liver cancer in male workers due to the definite carcinogenicity of hexavalent chromium. Significantly, an increased risk of spontaneous or threatened abortion was also found in female workers. In conclusion, these studies suggest that early detection of impaired reproductive function or impaired lung or liver function in female or male workers is essential for controlling occupational chromium poisoning in China.

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