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[Effect of propranolol gel on infantile hemangiomas].

[Article in Chinese]

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1
Department of General Surgery, Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, China.

Abstract

OBJECTIVE:

To evaluate the efficacy and security of propranolol gel in treatment of Infantile hemangiomas.

METHODS:

51 consecutive infants with hemangiomas from October 2010 to September 2011 in Department of General Surgery Fuzhou General Hospital of Nanjing Military Command were treated with propranolol hydrochloride 3% gel. Changes in hemangioma size, texture, color, tumor blood flow peak were recorded.

RESULTS:

The results were evaluated using Achauer system, responses of IHs to propranolol were considered scale I (poor) in 4 patient (17.24%), scale II (moderate) in 18 patients (24.14%), scale III (good) in 22 patients (44.83%) and scale IV (excellent) in 7 patients (13.79%). The response of superficial hemangiomas was significantly better than other hemangiomas (P < 0.05), and no significant differences in response among different primary sites (P > 0.05).

CONCLUSIONS:

Topical use of propranolol hydrochloride 3% gel is an effective option for superficial hemangiomas.

PMID:
23600126
[Indexed for MEDLINE]
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