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Chem Commun (Camb). 2013 May 25;49(42):4785-7. doi: 10.1039/c3cc38604j.

A comparative chemical-biological evaluation of titanium(IV) complexes with a salan or cyclopentadienyl ligand.

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  • 1Institute of Medicinal and Pharmaceutical Chemistry, Technische Universit√§t Braunschweig, Braunschweig, Germany.

Abstract

Titanium(IV) complexes with a salan or cyclopentadienyl ligand showed different biological behaviour concerning binding to biomolecules, cellular accumulation and intracellular distribution. Binding efficacy as well as trafficking on the cellular level are crucial parameters for their biological effects.

PMID:
23598498
DOI:
10.1039/c3cc38604j
[PubMed - indexed for MEDLINE]
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