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Phys Med Rehabil Clin N Am. 2013 May;24(2):371-92. doi: 10.1016/j.pmr.2012.11.003. Epub 2013 Jan 22.

Ambulation and Parkinson disease.

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1
Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, FL 32611, USA.

Abstract

Parkinson disease is a progressive neurodegenerative disorder characterized by a variety of motor and nonmotor features. This article reviews the problems of postural instability and gait disturbance in persons with Parkinson disease through the discussion of (1) the neuropathology of parkinsonian motor deficits, (2) behavioral manifestations of gait and postural abnormalities observed in persons with Parkinson disease, and (3) pharmacologic, surgical, and physical therapy-based interventions to combat postural instability and gait disturbance. This article advances the treatment of postural instability and gait disturbance by condensing up-to-date knowledge and making it available to clinicians and rehabilitation professionals.

PMID:
23598269
DOI:
10.1016/j.pmr.2012.11.003
[Indexed for MEDLINE]
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