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Rheum Dis Clin North Am. 2013 May;39(2):245-61. doi: 10.1016/j.rdc.2013.02.010. Epub 2013 Mar 14.

Behçet's syndrome.

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Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Cerrahpasa, Istanbul 34089, Turkey.


Behçet's syndrome (BS) shows a peculiar distribution, with a much higher prevalence in countries along the ancient Silk Road compared with rest of the world. BS also seems to follow a more severe course in ethnic groups with higher prevalence. Diagnosis depends on clinical findings. Criteria sets may not help in patients with less frequent types of involvement. Management strategies should be modified according to the age and sex of the patient and the organs involved. Being a serious health problem in endemic areas, BS also attracts global attention as a model to study inflammatory diseases of unknown cause.

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