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Asian Pac J Trop Biomed. 2013 Feb;3(2):156-62. doi: 10.1016/S2221-1691(13)60042-8.

Therapeutic potential of snake venom in cancer therapy: current perspectives.

Author information

1
Institute of Pharmacy, Nirma University, Ahmadabad 382 481 Gujarat, India.

Abstract

Many active secretions produced by animals have been employed in the development of new drugs to treat diseases such as hypertension and cancer. Snake venom toxins contributed significantly to the treatment of many medical conditions. There are many published studies describing and elucidating the anti-cancer potential of snake venom. Cancer therapy is one of the main areas for the use of protein peptides and enzymes originating from animals of different species. Some of these proteins or peptides and enzymes from snake venom when isolated and evaluated may bind specifically to cancer cell membranes, affecting the migration and proliferation of these cells. Some of substances found in the snake venom present a great potential as anti-tumor agent. In this review, we presented the main results of recent years of research involving the active compounds of snake venom that have anticancer activity.

KEYWORDS:

Anticancer agents; Apoptosis inducer; Cytotoxin; Snake venom

PMID:
23593597
PMCID:
PMC3627178
DOI:
10.1016/S2221-1691(13)60042-8
[Indexed for MEDLINE]
Free PMC Article

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