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Sci Signal. 2013 Apr 16;6(271):tr7. doi: 10.1126/scisignal.2003849.

Using partial least squares regression to analyze cellular response data.

Author information

1
Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA. kreeger@wisc.edu

Abstract

This Teaching Resource provides lecture notes, slides, and a problem set for a lecture introducing the mathematical concepts and interpretation of partial least squares regression (PLSR) that were part of a course entitled "Systems Biology: Mammalian Signaling Networks." PLSR is a multivariate regression technique commonly applied to analyze relationships between signaling or transcriptional data and cellular behavior.

PMID:
23592846
PMCID:
PMC4965874
DOI:
10.1126/scisignal.2003849
[Indexed for MEDLINE]
Free PMC Article

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