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J Child Neurol. 2014 Jun;29(6):782-8. doi: 10.1177/0883073813484358. Epub 2013 Apr 15.

Long-term outcomes of pediatric ischemic stroke in adulthood.

Author information

1
Children's Stroke Program, Division of Neurology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada jelbers@stanford.edu.
2
Children's Stroke Program, Division of Neurology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
3
Department of Child Health and Evaluative Sciences, The Hospital for Sick Children, University of Toronto, Toronto, Canada.

Abstract

This population-based study assesses the long-term impact of childhood stroke on function and independence in young adults. We undertook a cross-sectional outcome study of patients with arterial ischemic stroke and cerebral sinovenous thrombosis, beyond 18 years of age. We studied 26 patients; 21 arterial stroke, 5 cerebral sinovenous thrombosis, with 16 females. Mean age at assessment was 21.5 years, and mean follow-up time was 10.8 years. According to the modified Rankin Scale, final outcomes were 37% normal, 42% mild, 8% moderate, and 15% severe deficits. Risk factors for abnormal functional outcome included arterial ischemic stroke, presence of arteriopathy, and 1-year poststroke Pediatric Stroke Outcome Measure score ≥ 2 (P < .05). Most (77-84%) were independent in driving, relationships, and employment. Functional status at 1 year poststroke strongly predicts long-term outcome. Mental illness in one-quarter of young adults surviving childhood stroke represents an important direction for research.

KEYWORDS:

outcome; outcome measures; stroke

PMID:
23589374
DOI:
10.1177/0883073813484358
[Indexed for MEDLINE]

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