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Biochemistry (Mosc). 2013 Mar;78(3):221-30. doi: 10.1134/S0006297913030024.

Molecular functions of small regulatory noncoding RNA.

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1
Animal Science and Technology College, He Nan University of Science and Technology, Luoyang City, Henan Province, PR China. huangyong1979111@126.com

Abstract

Recently, using large-scale genomic sequencing, a great number of small noncoding RNAs (ncRNA) has been discovered. Short ncRNAs can be classified into three major classes--small interfering RNA (siRNA), microRNA (miRNA), and piwi-interacting RNA (piRNA). These short ncRNAs ranging from 20 to 300 nt in size are now recognized as a new paradigm of gene regulation for controlling many biological processes. In this paper, we review the biogenesis and recent research on the functions of small regulatory non-coding RNAs and aim at understanding their important functions in living organisms.

PMID:
23586714
DOI:
10.1134/S0006297913030024
[Indexed for MEDLINE]
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