Format

Send to

Choose Destination
See comment in PubMed Commons below
Zhonghua Yi Xue Za Zhi. 2013 Jan 1;93(1):44-7.

[Effect of dexmedetomidine in acute postoperative pain relief is independent of suppressing the hyperalgesia induced by remifentanil].

[Article in Chinese]

Author information

1
Department of Anesthesiology, First Hospital of Jiaxing, Jiaxing, China.

Abstract

OBJECTIVE:

To explore the effect of dexmedetomidine in acute postoperative pain and remifentanil-induced hyperalgesia.

METHODS:

From January 2011 to June 2012, 120 patients scheduled for elective abdominal surgery under general anesthesia were included in this study. All patients received intravenous remifentanil infusion during operation, and dexmedetomidine was given after anesthesia induction. The postoperative mechanical pain threshold, pain visual analog scale (VAS) score, morphine consumption, and score of sedation (Ramsay) was recorded.

RESULTS:

Relatively large-dose intraoperative remifentanil resulted in lower mechanical pain threshold and higher dose of postoperative morphine consumption. Dexmedetomidine reduced postoperative morphine consumption significantly, and increased Ramsay scores, but had no effect on mechanical hyperalgesia.

CONCLUSION:

Dexmedetomidine can alleviate the acute postoperative pain effectively, but the effect is not dependent on inhibiting remifentanil-induced hyperalgesia.

PMID:
23578454
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Chinese Medical Association Publishing House Ltd.
    Loading ...
    Support Center