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Chem Commun (Camb). 2013 May 18;49(40):4510-2. doi: 10.1039/c3cc39020a. Epub 2013 Apr 10.

Quantification of the Na+/K+ ratio based on the different response of a newly identified G-quadruplex to Na+ and K+.

Author information

1
National Laboratory for Molecular Sciences, Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Zhongguancun North 1st street 2, Beijing 100190, PR China.

Abstract

A G-quadruplex is identified which can exhibit two different motifs, respectively, corresponding to Na(+) and K(+). The relative amount of each motif is related to the Na(+)/K(+) ratio. Based on selective recognition of the G-quadruplex motifs by a cyanine dye aggregate, a method for both colorimetric and quantitative measurements of Na(+)/K(+) ratios is constructed.

PMID:
23577345
DOI:
10.1039/c3cc39020a
[Indexed for MEDLINE]

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