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Front Plant Sci. 2013 Apr 4;4:73. doi: 10.3389/fpls.2013.00073. eCollection 2013.

Recent progress in the development of metabolome databases for plant systems biology.

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RIKEN Plant Science Center Yokohama, Kanagawa, Japan.


Metabolomics has grown greatly as a functional genomics tool, and has become an invaluable diagnostic tool for biochemical phenotyping of biological systems. Over the past decades, a number of databases involving information related to mass spectra, compound names and structures, statistical/mathematical models and metabolic pathways, and metabolite profile data have been developed. Such databases complement each other and support efficient growth in this area, although the data resources remain scattered across the World Wide Web. Here, we review available metabolome databases and summarize the present status of development of related tools, particularly focusing on the plant metabolome. Data sharing discussed here will pave way for the robust interpretation of metabolomic data and advances in plant systems biology.


database; hypothesis generation; metabolite profiling; metabolomics; plant metabolism

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